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Tocris Bioscience™ MK6-83

TRPML channel activator

245.00€ - 924.00€

Specifications

Chemical Name or Material MK6-83
CAS 1062271-24-2
Synonym 5-Methyl-N-[2-(1-piperidinyl)phenyl]-2-thiophenesulfonamide
Solubility Soluble to 100mM in DMSO and to 20mM in ethanol
Molecular Formula C16H20N2O2S2
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Products 2
Product Code Brand Quantity Price Quantity & Availability  
Product Code Brand Quantity Price Quantity & Availability  
18703439
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Tocris Bioscience™
5547/10
10 mg
245.00€
10mg
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18756529
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Tocris Bioscience™
5547/50
50 mg
924.00€
50mg
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Description

Description

TRPML channel activator (EC50 = 110 nM). Also activates F408Δ and F465L TRPML mutants (EC50 values are 0.1 and 1.23 μM respectively). Restores endolysosomal trafficking and zinc homeostasis in lysosomes of mucolipidosis type IV (MLIV) mutant fibroblasts.
Specifications

Specifications

MK6-83
5-Methyl-N-[2-(1-piperidinyl)phenyl]-2-thiophenesulfonamide
C16H20N2O2S2
Solid
>98%
1062271-24-2
Soluble to 100mM in DMSO and to 20mM in ethanol
336.47
Bioactive Small Molecule
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Safety and Handling

Safety and Handling

Recommended Storage : Store at 4°C

SDS
Documents

Documents

Product Certifications

Research Use Only. Not For Human or Veterinary Use

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