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DiscoverX RBL-2H3 ADORA2A Gq Cell Line
The RBL-2H3 ADORA2A Gq Cell Line measures ADORA2A (GPCR) activation via an increase in intracellular calcium. This cell line ships as two vials of cryopreserved cells.
Brand: DiscoverX 95-1008C11
This item is not returnable.
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Description
The ADORA2A Gq cell line is a stable, engineered cell line for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This cell line enables assessment of ligand (e.g. adenosine, NECA) based activation of ADORA2A GPCR activity via detection of increasing levels of intracellular calcium. The included cell line overexpresses ADORA2A , a naturally Gq coupled GPCR. Upon activation of ADORA2A , the resulting calcium activity can be fluorescently assayed using the Calcium NoWash PLUS Detection Kit. This stable modified cell line is provided as two vials of cryopreserved cells.Specifications
Calcium Signaling | |
Cell Lines | |
2 Vials | |
NM_000675.4 |
RBL-2H3 | |
NECA | |
ADORA2A |
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