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DiscoverX Ready-to-Assay™ LPA2 Lysophospholipid Receptor Frozen Cells
The Ready-to-Assay™ LPA2 Lysophospholipid Receptor Frozen Cells measure LPAR2 (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.
Brand: DiscoverX HTS207RTA
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Description
The Ready-to-Assay™ LPA2 Lysophospholipid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. LPA) based activation of LPAR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress LPAR2 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of LPAR2 , the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.Specifications
| LPA2 | |
| LPA | |
| LPAR2 |
| Frozen Cells | |
| 2 Vials of Cells |
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