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DiscoverX Ready-to-Assay™ NPBW1 Neuropeptide B/W Receptor Frozen Cells
The Ready-to-Assay™ NPBW1 Neuropeptide B/W Receptor Frozen Cells measure NPBWR1 (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.
Brand: DiscoverX HTS180RTA
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Description
The Ready-to-Assay™ NPBW1 Neuropeptide B/W Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. neuropeptide B/W) based activation of NPBWR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress NPBWR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of NPBWR1 , the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.Specifications
NPBW1 | |
neuropeptide B/W | |
NPBWR1 |
Frozen Cells | |
2 Vials of Cells |
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