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DiscoverX Ready-to-Assay™ NPBW1 Neuropeptide B/W Receptor Frozen Cells

The Ready-to-Assay™ NPBW1 Neuropeptide B/W Receptor Frozen Cells measure NPBWR1 (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.

Brand:  DiscoverX HTS180RTA

Encompass

Product Code. 17365329

  • 1273.50€ / 2 ampoules
Estimated Shipment: 22-01-2025
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Description

Description

The Ready-to-Assay™ NPBW1 Neuropeptide B/W Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. neuropeptide B/W) based activation of NPBWR1 GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress NPBWR1 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of NPBWR1 , the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.
Specifications

Specifications

NPBW1
neuropeptide B/W
NPBWR1
Frozen Cells
2 Vials of Cells
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