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DiscoverX Ready-to-Assay™ S1P2 Lysophospholipid Receptor Frozen Cells
The Ready-to-Assay™ S1P2 Lysophospholipid Receptor Frozen Cells measure S1PR2 (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.
Brand: DiscoverX HTS078RTA
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Description
The Ready-to-Assay™ S1P2 Lysophospholipid Receptor Frozen Cells are a simple, thaw-and-assay cell format for use in studying drug candidates (small molecules or biologics) targeting GPCRs. This assay assesses ligand (e.g. S1P) based activation of S1PR2 GPCR activity via detection of increasing levels of intracellular calcium. The included cells overexpress S1PR2 alongside endogenous high levels of a promiscuous G-protein, coupling the receptor to the calcium signaling pathway. Upon activation of S1PR2 , the resulting calcium activity can be fluorescently assayed. Ready-to-assay kits consist of two vials of the cells in a convenient thaw-and-use format.Specifications
| S1P2 | |
| S1P | |
| S1PR2 |
| Frozen Cells | |
| 2 Vials of Cells |
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