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R&D Systems™ Recombinant Human/Mouse/Rat BMP-2 Protein
Extensive quality control produces industry leading bioactivity and lot-to-lot consistency that instills confidence in results and ensures reproducibility. Applications: Bioactivity
Brand: R&D Systems™ 355-BM-500/CF
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Description
Measured by its ability to induce alkaline phosphatase production by ATDC5 mouse chondrogenic cells. Binnerts, M.E. et al. (2004) Biochem. Biophys. Res. Commun. 315(2):272. The ED50 for this effect is 40-200 ng/mL.Specifications
| P12643 | |
| Lyophilized from a 0.2 μm filtered solution in Glycine, Sucrose, Tween™ 80 and Glutamic Acid. | |
| 13 kDa (monomer) | |
| 500 μg | |
| Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20°C to -70°C as supplied. 1 month, 2°C to 8°C under sterile conditions after reconstitution. 3 months, -20°C to -70°C under sterile conditions after reconstitution. | |
| Disulfide-linked homodimer | |
| BDA2, BMP2, BMP-2, BMP-2A, BMP2ABone morphogenetic protein 2A, bone morphogenetic protein 2, SSFSC | |
| Unconjugated | |
| Human, Mouse, Rat | |
| Reconstitute at 100 to 200 μg/mL in sterile 4 mM HCI. |
| Bioactivity | |
| 650 | |
| BMP-2 | |
| Chinese Hamster Ovary cell line,CHO-derived BMP-2 protein Gln283-Arg396 | |
| RUO | |
| <0.10 EU per 1 μg of the protein by the LAL method. | |
| BMP2 | |
| BMP-2 | |
| Recombinant | |
| 95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
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