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Tocris Bioscience™ SEA 0400

Potent Na+/Ca2+ exchanger (NCX) inhibitor.

Brand: Tocris Bioscience™ 6164/10

Product Code. 18725806

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Description

SEA 0400 is a potent Na+/Ca2+ exchanger (NCX) inhibitor. Inhibits NCX activity in rat astrocytes, microglia and cultured neurons, canine cardiac sarcolemmal vesicles and rat cardiomyocytes (IC50 values are 5 and 8.3, 33, 90 and 92 nM, respectively). Reduces infarct volumes and exhibits protective effects against myocardial ischemia in rats.

Specifications

Product Type	Inhibitor
CAS	223104-29-8
Formula Weight	371.38g/mol
For Use With (Application)	Na+/Ca2+ Exchanger Inhibitors

Target Proteins	Na+/Ca2+ Exchanger
Molecular Formula	C₂₁H₁₉F₂NO₃
Content And Storage	Store at -20°C
Quantity	10 mg

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Tocris Bioscience™ SEA 0400

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