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Thermo Scientific™ SMALP 300

Product Code. 30244991 Shop All Thermo Scientific Products
5 x 100 mg, Pack of 5
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Quantity:
1 g
5 x 100 mg
5 x 1 g
Unit Size:
1g
Pack of 5
This item is not returnable. View return policy
This item is not returnable. View return policy

Thermo Scientific SMALP 200 and SMALP 300 are styrene maleic acid (SMA) copolymers designed for the solubilization and stabilization of membrane proteins. These innovative products offer a streamlined approach to membrane protein isolation by combining solubilization and stabilization into a single step.

Thermo Scientific SMALP 200 and SMALP 300 are styrene maleic acid (SMA) copolymers designed for the solubilization and stabilization of membrane proteins.

These innovative products offer a streamlined approach to membrane protein isolation by combining solubilization and stabilization into a single step. The SMALP technology functions by interacting with the lipid bilayer and randomly encapsulating both the membrane proteins and their surrounding native lipids to form SMA lipid particles (SMALPs).

Features

  • Versatility—supplied as a 20% solution, allowing easy adjustment of concentration to suit specific experimental needs.
  • User-friendly—simply add at the optimal concentration and mix with homogenized preparation to initiate solubilization. 2.5% starting concentration is recommended.
  • Quality—produced using the highest quality polymer backbone

SMALP 200 and SMALP 300 represent a cutting-edge approach to membrane protein extraction, offering a detergent-free polymer-based method for isolating membrane proteins along with their surrounding lipid bilayer. This innovative technology provides researchers with a powerful tool for studying membrane proteins in their native lipid environment, potentially leading to more accurate structural and functional analyses.

SMALP is a registered trademark of Aurorium.

Disclaimer

The use of this styrene maleic acid copolymer (SMA) product for the manufacture of styrene maleic acid copolymer - lipid particles (SMALP), and the use of SMALP, are covered by one or more of the following patents owned by Malvern Cosmeceutics Limited: US 8623414, EP 1890675, GB 2426703. AU 2006253886, JP 5142898, IN 261468, CN ZL200680018957.2 and CA 2,611,144 and by the University of Birmingham: US 8754168.

The purchaser is licensed under those patents to use the SMA for the manufacture of SMALP and to use the SMALP for the purpose of research and development of proteins, including their production (including purification and solubilization), screening testing, analysis, characterization (including structural analysis and characterization), including for the purpose of drug screening and for the purpose of in vitro diagnostics, but not for the purpose of delivery of agents to humans or other animals for therapeutic, diagnostic (including in vivo diagnostics) or prophylactic purposes, which uses are specifically prohibited.

TRUSTED_SUSTAINABILITY

Specifications

Product Type Polymer
Formula Weight 10,000 Da
Sensitivity Sensitive to light
Content And Storage Store at 4°C
Form Liquid
Product Line Thermo Scientific™
For Use With (Application) Structure/Function
Reagent Type Extraction and stabilization
Purification Target Membrane proteins
Quantity 5 x 100 mg
Composition 100 mg active polymer in a 20% solution
pH 8
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For Research Use Only. Not for use in diagnostic procedures.

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