missing translation for 'onlineSavingsMsg'
Learn More
  1. Home
  2. Products
  3. Protein Analysis Reagents
  4. Bioactive Small Molecules
  5. Tocris Bioscience™ uPSEM 817 tartrate
  6. 18005742

Tocris Bioscience™ uPSEM 817 tartrate

Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant

Brand:  Tocris Bioscience™ 6866/5

 View more versions of this product

Product Code. 18005742

  • 278.00€ / 5mg
Estimated Shipment: 30-01-2025
to see stock.
Explore more special offers
Add to basket
This item is not returnable. View return policy

Description

Description

uPSEM 817 tartrate is a selective ultrapotent PSEM (uPSEM) agonist for α7L131G,Q139L,Y217F-GlyR (PSAM4-GlyR) and PSAM4-5-HT3 chimeric ion channels (EC50 values are 0.3 and 0.5 nM, respectively). Suppresses firing of layer 2/3 cortical neurons expressing PSAM4-GlyR in brain slices. Increases contralateral rotation in mice expressing PSAM4-GlyR unilaterally in the substantia nigra reticulata (LED 0.1 mg/kg).
Specifications

Specifications

2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate
5 mg
C16H19N3O.C4H6O6
98%
2341833-14-3
Pharmacologically Selective Effector Molecules/PSEM
419.43
Product Suggestions

Product Suggestions

Videos
SDS
Documents

Documents

Certificates
Special Offers

Special Offers

Product Content Correction

Your input is important to us. Please complete this form to provide feedback related to the content on this product.

Product Title

By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.

Thank You! Your feedback has been submitted. Fisher Scientific is always working to improve our content for you. We appreciate your feedback.