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Tocris Bioscience™ uPSEM 817 tartrate
Highly potent and selective PSAM4-GlyR and PSAM4-5-HT3 chimeric ion channel agonist; brain-penetrant
278.00€ - 1070.00€
Specifications
| Chemical Name or Material | 2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate |
|---|---|
| CAS | 2341833-14-3 |
| Target | Pharmacologically Selective Effector Molecules/PSEM |
| Molecular Formula | C16H19N3O.C4H6O6 |
| Formula Weight | 419.43 |
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|---|---|---|---|---|---|---|---|---|---|
| Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
|
18759836
|
Tocris Bioscience™
6866/25 |
25 mg |
1070.00€
25mg |
Estimated Shipment: 30-01-2025
Log in to see stock. |
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|
18005742
|
Tocris Bioscience™
6866/5 |
5 mg |
278.00€
5mg |
Estimated Shipment: 30-01-2025
Log in to see stock. |
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Description
Selective ultrapotent PSEM (uPSEM) agonist for α7L131G,Q139L,Y217F-GlyR (PSAM4-GlyR) and PSAM4-5-HT3 chimeric ion channels (EC50 values are 0.3 and 0.5 nM, respectively). Suppresses firing of layer 2/3 cortical neurons expressing PSAM4-GlyR in brain slices. Increases contralateral rotation in mice expressing PSAM4-GlyR unilaterally in the substantia nigra reticulata (LED 0.1 mg/kg).Specifications
| 2-Propoxy-7,8,9,10-tetrahydro-6 H-6,10-methanoazepino[4,5-g]quinoxaline L-tartrate | |
| Pharmacologically Selective Effector Molecules/PSEM | |
| 419.43 |
| 2341833-14-3 | |
| C16H19N3O.C4H6O6 | |
| 98% |
Safety and Handling
Recommended Storage : Store at -20°C
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