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For cortical stem cell expansion and differentiation into neurons, astrocytes and oligodendrocytes
The KILR™ THP-1 Cell Pool allows for assay of effector-induced cell death by a variety of immune mechanisms. This cell pool ships as two vials of cryopreserved cells.
For cortical stem cell expansion and differentiation into neurons, astrocytes and oligodendrocytes
For use as a feeder layer when culturing embryonic or induced pluripotent stem cells
The ChemiScreen™ CB1 Cannabinoid Receptor Membrane Preparation allows measurement of ligand binding to CNR1 GPCR via radioligand binding assays, or GPCR activity via GTPγS assay. Membrane preps contain 1mL of 1mg/mL frozen membranes.
The PathHunter™ EDG5 Activated GPCR Internalization U2OS Cell Line measures EDG5 (GPCR) internalization via early-endosome localization. This cell line ships as two vials of cryopreserved cells.
The PathHunter™ U2OS PTGER1 β-Arrestin Cell Line measures PTGER1 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.
The PathHunter™ U2OS IL1RL1/IL1RAP Dimerization Cell Line measures ligand-induced dimerization of IL1RL1/IL1RAP . This cell line ships as two vials of cryopreserved cells.
The PathHunter™ U2OS EphB3 Functional Assay measures EphB3 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This cell line ships as two vials of cryopreserved cells.
The ChemiScreen™ PK2 Prokineticin Receptor Membrane Preparation allows measurement of ligand binding to PROKR2 GPCR via radioligand binding assays. Membrane preps contain 1mL of 1mg/mL frozen membranes.
The ChemiScreen™ ChemR23 Chemoattractant Receptor Stable Cell Line measures CMKLR1 (GPCR) activation via an increase in intracellular calcium. This cell line ships as two vials of cryopreserved cells.