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1 – 15 of 37 results
1

Tocris Bioscience™ MZ 1

(+)-JQ1 based Degrader (PROTAC™) that selectively degrades BRD4

2

Tocris Bioscience™ Filipin III

Polyene antibiotic; inhibits formation of pathological isoform of prion protein

3

Tocris Bioscience™ Ned K

NAADP signaling inhibitor

Content And Storage Store at -20°C
Product Type Inhibitor
Solubility Soluble to 50mM in DMSO
Color Cream
For Use With (Application) Prevents Ca2+ oscillations
Molecular Formula C31H31N5O3
Formula Weight 521.61g/mol
4

Tocris Bioscience™ Cinacalcet hydrochloride

Low molecular weight, organic compound that may help regulate biological process.

Content And Storage Store at -20°C
CAS 364782-34-3
Target Proteins Calcium-Sensing Receptor
Product Type Inhibitor
For Use With (Application) Calcium-Sensing Receptor Agonists
Molecular Formula C22H22F3N.HCl
Formula Weight 393.87g/mol
6

Tocris Bioscience™ Bosentan

High affinity dual ETA and ETB receptor antagonist;orally bioavailable

Content And Storage Store at 4°C
CAS 147536-97-8
Target Proteins Non-selective Endothelin Receptor
Product Type Antagonist
For Use With (Application) Non-selective Endothelin Receptor Antagonists
Molecular Formula C27H29N5O6S
Formula Weight 551.61g/mol
7

Tocris Bioscience™ AR-C 69931 Tetrasodium Salt

Low molecular weight, organic compound that may help regulate biological process.

8

Tocris Bioscience™ Entecavir

Potent and selective hepatitis B virus inhibitor

Content And Storage Store at -20°C
Description 2-Amino-1,9-dihydro-9-[(1 S,3 R,4 S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6 H-purin-6-one
CAS 142217-69-4
Product Type Inhibitor
Synonym BMS 200475, SQ 34676
For Use With (Application) RNA/DNA Polymerase Inhibitors
Molecular Formula C12H15N5O3
Formula Weight 277.28
9

Tocris Bioscience™ (±)-ML 209

RORγt inverse agonist; suppresses Th17 cell differentiation

CAS 1334526-14-5
Product Type Inhibitor
Solubility Soluble to 100mM in DMSO
Color White
Molecular Formula C25H31NO6
11

Tocris Bioscience™ VH 298

High-affinity inhibitor of VHL

Content And Storage Store at -20°C
Target Proteins Ubiquitin Ligase (E3)
Product Type Inhibitor
For Use With (Application) Ubiquitin Ligase (E3) Inhibitors
Molecular Formula C27H33N5O4S
Formula Weight 523.65g/mol
12

Tocris Bioscience™ SR 9243

Selective LXR inverse agonist

Content And Storage Store at 4°C
CAS 1613028-81-1
Product Type Inhibitor
Solubility Soluble to 20mM in DMSO
Color White
For Use With (Application) Inhibits IL-1β
Molecular Formula C31H32BrNO4S2
Formula Weight 626.62g/mol
15

Tocris Bioscience™ B I09

IRE1 endonuclease inhibitor; cell permeable

Content And Storage Store at -20°C
CAS 1607803-67-7
Product Type Inhibitor
Solubility Soluble to 50mM in DMSO
Color Beige
For Use With (Application) Inhibits Rnase
Molecular Formula C16H17NO5
Formula Weight 303.31g/mol