General Cell Lines and Cell Cultures
General Cell Lines and Cell Cultures
Novus Biologicals™ Dicer knockout Mouse Embryonic Stem Cells
Used in common research applications
DiscoverX PathHunter™ Jurkat NFAT Pathway Reporter Cell Line
The PathHunter™ Jurkat NFAT Pathway Reporter Cell Line measures NFAT pathway activation through detection of induced expression levels of a tagged reporter protein. This cell line ships as two vials of cryopreserved cells.
Gibco™ CHO DG44 Cells (cGMP banked) and Media Kit
CHO DG44 Cells (cGMP banked) and Media Kit
DiscoverX KILR™ PANC-1 Cell Pool
The KILR™ PANC-1 Cell Pool allows for assay of effector-induced cell death by a variety of immune mechanisms. This cell pool ships as two vials of cryopreserved cells.
DiscoverX ChemiScreen™ ETB Endothelin Receptor Membrane Preparation
The ChemiScreen™ ETB Endothelin Receptor Membrane Preparation allows measurement of ligand binding to EDNRB GPCR via radioligand binding assays. Membrane preps contain 1mL of 1mg/mL frozen membranes.
DiscoverX KILR™ MOLT-4 Cell Pool
The KILR™ MOLT-4 Cell Pool allows for assay of effector-induced cell death by a variety of immune mechanisms. This cell pool ships as two vials of cryopreserved cells.
Novus Biologicals™ DGCR8 Knockout MEF Cells
Applications: In vitro assay
DiscoverX ChemiScreen™ CB1 Cannabinoid Receptor Membrane Preparation
The ChemiScreen™ CB1 Cannabinoid Receptor Membrane Preparation allows measurement of ligand binding to CNR1 GPCR via radioligand binding assays, or GPCR activity via GTPγS assay. Membrane preps contain 1mL of 1mg/mL frozen membranes.
DiscoverX PathHunter™ PTHR2 Total GPCR Internalization U2OS Cell Line
The PathHunter™ PTHR2 Total GPCR Internalization U2OS Cell Line measures PTHR2 (GPCR) internalization via early-endosome localization. This cell line ships as two vials of cryopreserved cells.
DiscoverX InCELL Hunter™ U2OS Bcl2L1-Bim Protein Binding Cell Line
The InCELL Hunter™ U2OS Bcl2L1-Bim Protein Binding Cell Line measures protein binding via compound-induced binding partner disruption and degradation. This cell line ships as two vials of cryopreserved cells.
DiscoverX InCELL Hunter™ HEK 293 RIPK2 Kinase Binding Cell Line
The InCELL Hunter™ HEK 293 RIPK2 Kinase Binding Cell Line measures target engagement via compound-induced stabilization of RIPK2 target protein. This cell line ships as two vials of cryopreserved cells.
DiscoverX PathHunter™ U2OS TYRO3 Functional Assay
The PathHunter™ U2OS TYRO3 Functional Assay measures TYRO3 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This cell line ships as two vials of cryopreserved cells.
DiscoverX PathHunter™ CHO-K1 GPR34 β-Arrestin Cell Line
The PathHunter™ CHO-K1 GPR34 β-Arrestin Cell Line measures GPR34 (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.
DiscoverX cAMP Hunter™ CHO-K1 ADORA1 Gi Cell Line
The cAMP Hunter™ CHO-K1 ADORA1 Gi Cell Line measures ADORA1 (GPCR) activity via decreased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.
DiscoverX cAMP Hunter™ CHO-K1 CHRM2 Gs Cell Line
The cAMP Hunter™ CHO-K1 CHRM2 Gs Cell Line measures CHRM2 (GPCR) activity via increased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.