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The PathHunter™ Jurkat NFAT Pathway Reporter Cell Line measures NFAT pathway activation through detection of induced expression levels of a tagged reporter protein. This cell line ships as two vials of cryopreserved cells.
The KILR™ MOLT-4 Cell Pool allows for assay of effector-induced cell death by a variety of immune mechanisms. This cell pool ships as two vials of cryopreserved cells.
The ChemiScreen™ CB1 Cannabinoid Receptor Membrane Preparation allows measurement of ligand binding to CNR1 GPCR via radioligand binding assays, or GPCR activity via GTPγS assay. Membrane preps contain 1mL of 1mg/mL frozen membranes.
The cAMP Hunter™ CHO-K1 MCHR1 Gi Cell Line measures MCHR1 (GPCR) activity via decreased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.
The cAMP Hunter™ CHO-K1 PPYR1 (NPY4R) Gi Cell Line measures PPYR1 (GPCR) activity via decreased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.
The ChemiScreen™ S1P4 Lysophospholipid Receptor Stable Cell Line measures S1PR4 (GPCR) activation via an increase in intracellular calcium. This cell line ships as two vials of cryopreserved cells.
The cAMP Hunter™ CHO-K1 DRD2S (Short Isoform) Gi Cell Line measures DRD2S (GPCR) activity via decreased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.
The CHO-K1 EDG3 Gq Cell Line measures EDG3 (GPCR) activation via an increase in intracellular calcium. This cell line ships as two vials of cryopreserved cells.
The InCELL Hunter™ A549 HCK Kinase Binding Cell Line measures target engagement via compound-induced stabilization of HCK target protein. This cell line ships as two vials of cryopreserved cells.
The PrecisION™ hKv1.8 Recombinant Stable Cell Line measures Kv1.8 ion channel activity via electrophysiological measurements. This cell line ships as two vials of cryopreserved cells.
The PrecisION™ hKv2.1/hKv9.2 Recombinant Stable Cell Line measures Kv2.1/Kv9.2 ion channel activity via electrophysiological measurements. This cell line ships as two vials of cryopreserved cells.
The ChemiScreen™ BLT1 Leukotriene Receptor Membrane Preparation allows measurement of ligand binding to LTB4R GPCR via radioligand binding assays. Membrane preps contain 1mL of 1mg/mL frozen membranes.