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The PathHunter™ Jurkat NFAT Pathway Reporter Cell Line measures NFAT pathway activation through detection of induced expression levels of a tagged reporter protein. This cell line ships as two vials of cryopreserved cells.
The KILR™ MOLT-4 Cell Pool allows for assay of effector-induced cell death by a variety of immune mechanisms. This cell pool ships as two vials of cryopreserved cells.
The ChemiScreen™ CB1 Cannabinoid Receptor Membrane Preparation allows measurement of ligand binding to CNR1 GPCR via radioligand binding assays, or GPCR activity via GTPγS assay. Membrane preps contain 1mL of 1mg/mL frozen membranes.
The PathHunter™ U2OS PD-L1 Ligand Cell Line works with Checkpoint signaling cell lines to induce SH2 domain protein recruitment. This cell line ships as two vials of cryopreserved cells.
The ChemiScreen™ FP Prostanoid Receptor Stable Cell Line measures PTGFR (GPCR) activation via an increase in intracellular calcium. This cell line ships as two vials of cryopreserved cells.
The PathHunter™ DDR1 Functional Assay measures DDR1 receptor tyrosine kinase activity via ligand-induced SH2 domain protein recruitment. This cell line ships as two vials of cryopreserved cells.
The Ready-to-Assay™ EP2 Prostanoid Receptor Frozen Cells measure PTGER2 (GPCR) activation via an increase in intracellular calcium. Ready-to-Assay kits contain two vials of thaw-and-use cells.
The ChemiBrite™ GPR120 Receptor Stable Cell Line measures FFAR4 (GPCR) activation via an increase in intracellular calcium. This cell line ships as two vials of cryopreserved cells.
The PathHunter™ HEK 293 KDR/KDR Dimerization Cell Line measures ligand-induced dimerization of KDR/KDR . This cell line ships as two vials of cryopreserved cells.
The PathHunter™ CHO-K1 NPY2R β-Arrestin Cell Line measures NPY2R (GPCR) activity via recruitment of β-Arrestin2. This cell line ships as two vials of cryopreserved cells.
The cAMP Hunter™ CHO-K1 HTR1A Gi Cell Line measures HTR1A (GPCR) activity via decreased levels of intracellular cAMP. This cell line ships as two vials of cryopreserved cells.
The PrecisION™ hKv3.1 Recombinant Stable Cell Line measures Kv3.1 ion channel activity via electrophysiological measurements. This cell line ships as two vials of cryopreserved cells.